Choline

What is Choline?

Choline is a water-soluble nutrient that is closely related to a class of essential vitamins which include folate and vitamins in the vitamin B complex family. These essential vitamins carry out thousands of important functions throughout the body and equivalently, choline is very important in facilitating various activities which include; efficient liver functioning, it supports nerve functions, it regulates metabolism, it maintains the body’s energy levels, it facilitates the muscle movement and it ensures normal brain development and functioning. Choline is a vital component that is mixed into the MIC injections, abbreviated as the “C” in MIC. It is also used in many other Lipotropic injections in different combinations.

Choline in Detoxification

Choline also plays an important role in detoxification, nerve signaling and the synthesis of DNA through the process of Methylation. It facilitates the efficient functioning of acetylcholine which is a key neurotransmitter that oversees effective communication between the nerves which help the body muscles to move. Acetylcholine also slows down aging and it regulates numerous other processes in the body system.

Choline is not actually a vitamin or a mineral, but it is an essential micronutrient that is required for many important functions in the body especially that of normal brain development and functioning. For this reason, it is very beneficial to avoid choline deficiency so that you can support all the functions in different systems in your body.

Our bodies can manufacture choline in the liver but we must also obtain a significant amount of exogenous choline from natural food substances or supplements. Choline can be found in animal liver, eggs, salmon, breast milk, beef, cauliflower, beans, fish, nuts, peas, wheat germs, and spinach.

 

Symptoms of Choline Deficiency

Even though Choline can be obtained from a variety of food sources, there is evidence that not all of it is absorbed into the body. Some people have some factors, that are presumed to be genetic, which inhibit the absorption of choline into their bodies and makes it even harder. This can ultimately lead to a choline deficiency. Some signs and symptoms of choline deficiency include memory loss, fatigue and low energy levels, cognitive deterioration, unstable moods, nerve damage, muscle aches and learning disabilities.

 

Individuals with a condition known as fatty liver disease are at a higher risk of suffering from choline deficiency. This is a condition that leads to excessive fat deposits on various parts of the body or the whole body. Fatty liver disease is common in individuals who are obese, diabetic individuals, people who consume excess alcohol and people with various diseases which can interfere with the metabolism of fat in the body. This condition is however totally reversible.

Uses of Choline

Choline is clinically used to treat Liver disease that can develop due to parenteral nutrition (this is exclusive feeding through the veins), in patients with choline deficiency. Administering choline intravenously can help to manage this condition.

Various scientific evidence also points out that taking choline can lessen the symptoms of asthma and substantially reduce asthma-related problems for some people. These studies also showed that choline can reduce the urge and need to use bronchodilators. Higher doses of about 3 grams daily proved to be more effective than lower doses of about 1.5 grams.

Choline can be used to minimize the chances of neural tube defects in pregnant women. Research has proven that women who consume a lot of choline during their conception period have minimal risks of giving birth to babies with neural tube defects.

Choline cannot be used to treat Alzheimer’s disease and it does not lessen the symptoms of this disease.

Taking choline does not lessen fatigue during training or exercise and it has no effect on athletic performance so it should not be used with the aim of attaining these results.

Previous research had suggested that administering choline orally had the ability to improve motor functions in individuals with brain ataxia which is a condition of the brain. However, the latest research has dismissed these claims. Choline is also ineffective in managing memory loss due to old age and treating schizophrenia.

There have been numerous claims that choline can be used to manage a number of conditions but unfortunately, there is unreliable evidence to support these claims. Some of these conditions include; allergies, bipolar disorder, bronchitis, poor mental performance, seizures, hepatitis, some liver disorders, depression, high cholesterol, Tourette’s syndrome and Huntington’s chorea.

Currently, there is insufficient information on the interactions of choline with other substances but so far, choline has proven to be very safe.

Side effects of Choline

Choline is generally safe for most adults especially when administered orally or given intravenously in the required and appropriate amounts. Choline is however possibly harmful to both adults and children when taken in higher doses over the daily upper intake level. An overdose is likely to lead to negative side effects that are associated with a fishy body odor, sweating, vomiting and gastrointestinal distress.

There are suggestions that increasing your dietary intake of choline can increase the risks of colon cancer and rectum cancer. But more studies are being carried out to ascertain this.

Pregnancy and Breastfeeding

Choline is very safe when taken orally in doses of about 3 grams which is recommended for pregnant women under 18 years old and 3.5 grams for pregnant women who are 19 years and older. This dosage should not be exceeded in order to avoid any negative effects. There is insufficient information concerning the use of choline by pregnant and lactating mothers but it is better to stick on the recommended doses so that you can keep yourself and your infant safe.

Recommended dosage for Choline

The recommended dosage of choline for asthma patients is about 500mg to 1000 mg daily.

The daily upper intake levels for children under 8 years is 1 gram, that for children between 9 years to 13 years is 2 grams and that for teenagers up to 18 years is 3g. Adults above 18 years can take up to 3.5 grams.

Conclusion

Just like the essential vitamins of the vitamin B complex family, choline is very important for a majority of body functions. You can easily find this drug in our pharmacy and the best part is that we can compound it in dosages that will work best for you. For more information on this medication and its administration, feel free to contact us.