GHRP-2 / GHRP-6 / Sermorelin Acetate Injection

What is Sermorelin GHRP-2 / GHRP-6 / Sermorelin Acetate Injection

Sermorelin Acetate is prescribed for the stimulation of the pituitary gland and increase the natural production of growth hormone (HGH), within the limits of endocrine system capacity.

The dosage presentation available for GHRP-2 / GHRP-6 / Sermorelin Acetate is an Injection Solution. Absolute Pharmacy’s injection solutions are combined under the strict standards of USP 797 for the sterile composition of each batch. Our quality assurance process ensures the uniformity of each compound dispensed.

GHRP-2 is a peptide that is only a member of the large family of peptide growth factors and is very similar in structure and function to GHRP-6.

Both act by stimulating the pituitary gland which causes an increased release of GH. GHRP-2 is used for a variety of medical problems such as low GH production and natural weight gain promoting abnormally thin individuals.

General information on GHRP 2 & GHRP 6:

GHRP-2 has been extensively studied for its utility and action as growth hormone secretagogue (GHS), meaning it stimulates the secretion of growth hormone. This is a hexapeptide with potent properties. GHRP-2 is basically a sterile white lyophilized powder. It is considered to be the most potent classes in the GHRP family.

This peptide has been shown to be useful in adults and can be given through the oral, intravenous and intranasal route. GHRPs is not simply substituted for GHRH, instead, GHRP-6 is an artificial activator of a receptor called Secretagogues newly discovered receptor (GHS-R).

While both peptides of the amino acid release GH, there is a noticeable difference in GHRP-6, this speeds up digestion taking into account a larger consumption of food. It is worth adding that this particular peptide is a first generation GHRP. Get the absolute most value from GH releases.

Mechanism of action:

While GHRH stimulates adenylate cyclase activity and increases cAMP production (21), synthetic GHs do not bind to the pituitary receptor for GHRH (22), generating depolarization and inhibition of potassium channels in somatotropic cells, activating the Protein kinase C and increasing the hydrolysis of phosphatidylinositol (7,9,21,22).

Recently, the existence of a specific high-affinity binding site in pituitary membranes has been shown to mediate the activity of these secretagogues. Accordingly, the receptor mediating the GH-secreting activities of GHRP-6, L-692,429 and L-163,191 (MK-0677) is bound to a G protein. In addition, the same authors indicate that they have characterized A similar receptor in hypothalamic membranes.

Drug Name: Sermorelin

It is a hormonal peptide treatment known as a secretagogue that induces the secretion of human growth hormone. For this reason, Sermorelin is known as a growth hormone releasing agent.

General information:

Sermorelin Acetate (also known as GRF 1-29) is an analog of growth hormone releasing hormone (GHRH). GHRH is produced in the brain (in the hypothalamus) and is subsequently transported through the bloodstream into the pituitary gland where its role is to stimulate and release growth hormone (GH).

Sermorelin (GRF 1-29) has a short molecule, comprising 29 amino acids (for example, for comparison – the HGH molecule is substantially larger – comprising 191 amino acids). The Sermorelin GRF 1-29 sequence is a part of the endogenous human GHRH and is currently considered as the short synthetic peptide which possesses the full range of GHRH activity.

Sermorelin is often used as an effective anti-aging therapy product in men, usually in relation to testosterone. Sermorelin can be considered as an excellent alternative to recombinant growth hormone (rhGH), especially in people looking for similar hormones with anti-aging effects for achieving anti-aging goals. Sermorelin is so safe that in the USA. It is prescribed for children as a treatment for growth hormone deficiency or for patients who need to lose weight quickly and efficiently.

Mechanism of action:

Sermorelin stimulates the patient’s own pituitary gland by binding to specific receptors that increase the production and secretion of endogenous or own HGH from the body. Because Sermorelin increases the natural endogenous hormones by stimulating the pituitary gland is considered as an excellent treatment.

Sermorelin stimulates your pituitary gland to make HGH more natural. Your pituitary gland will only produce what you need and no more. Its secretory effects are regulated by the pituitary gland through the negative feedback loop and the release of somatostatin so as to avoid the side effects of too much endogenous HGH.

Cell and tissue exposure to HGH released by the pituitary under the influence of Sermorelin is a natural physiological response to doses administered mimicking normal human physiology. By stimulating the pituitary gland it retains more of the neuroendocrine hormone growth hormone and loop feedback that deteriorates over time due to the aging process.

The pituitary stimulation resulting from Sermorelin injections helps mitigate the endocrine deficiency that occurs during the aging composition of the juvenile body and physiology. GH peptide therapy provides patients with all the benefits of HGH replacement therapy.

What is this medicine used for?

It is used in adults who take hormone replacement therapy for human growth hormone. A patient can take GH peptides alone or together with injections of human growth hormone to enhance the effects of bio-identical therapy.

Precautions:

Make sure your doctor knows if you are pregnant or breastfeeding. Your doctor will need to know if you have diabetes, hypothyroidism, or a history of problems with your blood sugar.

The presence of other medical problems may affect the use of this medication. Be sure to tell your doctor if you have any other medical problems such as interactions with drugs or other interactions.

What to do if you forget a dose:

In case you miss a dose, take it as soon as you notice it. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take extra doses to make up for a forgotten dose.

If you are losing your doses regularly, it is recommended to set an alarm or ask a family member to remind you. Please consult your doctor to discuss changes to the dosing schedule or a new schedule to compensate for missed doses if you have missed many doses recently.

In all studies, it has been observed that Sermorelin does not modify uterine activity, nor does it present sensitization phenomena on this organ. All studies show that it shows no mutagenic activity.

Adverse reactions:

Chest tightness or fast heart rate.
Fainting or fainting.
Redness, pain, blisters, or rash at the injection site.

Recommendations for storage:

It should be kept refrigerated at 2C to 8C. During the period of conservation there are no qualitative or quantitative changes of the active principle, so its pharmacological action remains unchanged.

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