During our younger years, there is an abundant production of growth hormone releasing hormone (GHRH) which is used to sustain and nourish the function, form and overall health of our body.

However, as we age, GHRH declines which results to a decrease in the secretion of pituitary human growth hormone (HGH). Eventually, the HGH levels goes down and production stops. When this happens, the HGH insufficiencies increase and age-related symptoms such as brittle and dry hair, dry skin, lethargy, reduction of lean body mass, poor cognitive function, and slower or difficult recovery from injuries, surgeries and other strenuous activities are started to be experienced. As a result, stamina, vitality and overall health is diminished.

Sermorelin is a bio-identical hormone peptide containing the first 29 amino acids that make up the growth hormone in our bodies. Considered as a revolutionary drug, Sermorelin addresses aging problems by stimulating the pituitary gland to naturally produce and secrete increased amounts of growth hormone, which then aids in an array of beneficial results such as increased energy levels, enhanced sleep quality, strengthened bone and muscle, regulated cellular activities and reversed aging process.

Due to its powerful and significant effect on HGH secretion, Sermorelin is able to restore and regenerate the HGH levels and imitate its effects, boosting one’s health span and significantly improving quality of life. Approved by the FDA under the brand name Geref and available only by prescription, Sermorelin is a safe and effective alternative to HGH without its harmful side effects and high cost. It can be used by both children and adults to treat growth hormone deficiency. Note however that though considered as the best HGH supplement in the market, it will not be as effective in people with high HGH levels deficiency. It is then recommended that an HGH therapy should be done first prior to starting Sermorelin treatment.



  • The growth hormone releasing hormone or GHRH is naturally processed in the hypothalamus. It sends signals to the pituitary gland which then controls and regulates the natural release of growth hormone among many other functions. However, problems may occur in the function of GHRH. There are instances wherein it is not being released enough, problem with the destination pituitary gland occurs, or the pituitary gland does not function properly. When the mechanism to produce GHRH malfunctions, the process of aging starts at a faster rate. This is where Sermorelin treatment comes in. Sermorelin Acetate works as a biologically engineered version of GHRH, imitating the function and effects of the hypothalamic peptide. GHRH travels to the pituitary gland, attaches to its receptors and signals to produce HGH naturally. On the other hand, when Sermorelin is administered, it travels through the bloodstream, binds to the GHRH receptors and stimulates the somatotroph cells to produce and secrete HGH. As a result, Sermorelin achieves similar effects of HGH such as enhanced energy levels, increased sex drive, increased muscle mass and the aging process is slowed down or reversed, without the negative effects of HGH.

  • Sermorelin injections are safe to be taken by the following:

    • Children with growth hormone deficiency or dwarfism.
    • Adults who are suffering from growth hormone deficiency and who would like to enhance their appearance, slow down and reverse the signs of aging, and improve their health.

    However, should you have any of the following conditions, inform your medical provider first prior to starting this peptide therapy:

    • If you are pregnant, planning to become pregnant, or breast-feeding. It is not known if this drug can be passed to the fetus and be excreted through breast milk.
    • If you have or had a head or brain injury or illness, and a growth hormone deficiency following an intracranial lesion.
    • If you have untreated hypothyroidism. Thyroid hormone determinations should be performed first prior to usage of Sermorelin.
    • If you are taking any prescription or nonprescription medicine, and herbal or dietary supplement.
    • If you have allergies to medicines, foods, or other substances especially Sermorelin Acetate.

  • The goal of Sermorelin therapy is to induce the pituitary gland to produce more HGH naturally. By doing so, several issues that develop due to HGH deficiency can be reversed, stopped and treated. Some of the benefits of Sermorelin injections include:

    • Enhances cardiovascular and immune function.
    • Enhances cognitive function including alertness, focus, mental clarity, sharpness, and memory.
    • Stops and reverses the effects of aging.
    • Improves skin quality, elasticity and higher collagen density and thickens hair and nails
    • Regenerates nerve tissues and accelerates wound healing.
    • Increases protein synthesis and stimulates the growth of all internal organs .
    • Increases energy, vitality, endurance, strength and physical performance while lessening fatigue.
    • Improves sexual drive and performance.
    • Increases lean muscle mass through new muscle cells production and reduces fat and fatty acids including abdominal fat.
    • Provides joint and muscle pain relief for patients with arthritis and chronic pain.
    • Increases calcium retention, strengthens and improves bone and mineral density.
    • Improves sleep quality and promotes non-REM slow wave sleep.
    • Reduces risk for developing metabolic diseases including diabetes.
    • Improves sexual drive and performance.
    • Enhances body composition, sense of well-being and overall quality of life.
  • Sermorelin Acetate can be used as treatment for conditions deemed necessary by your doctor including the following:

    • Dwarfism
    • Prevention of HIV-induced weight loss.
    • Maladaptive changes in the body composition.
    • MFor increasing insulin like growth factor 1 (IGF-1).
    • To be administered once daily at any time of the day for as long as the treatment is prescribed.
    • Sermorelin is best to be administered at night to maximize its benefits. By injecting before bedtime, it facilitates better and deeper sleep quality, signals the nocturnal release of more HGH, and stimulates the pituitary gland.
    • When administered in the morning, the patient will have to skip breakfast and risk falling asleep throughout the day because of its drowsy effect.
    • When injected in the afternoon, the risk of reducing the potency of this drug becomes high due to the highest volume of food (fats and carbohydrates) consumed at this time.
    • Timing of food intake is very important. Administering this drug should be at least 30 minutes before or after eating to avoid interfering with the glucose levels.
    • To maximize benefits and achieve optimal results, usage of this drug should range from 90 to 180 days.
    • Do not start, stop or change the dose of your medicine without your doctor’s approval.
  • All medicines may cause side effects. For Sermorelin, no generalized allergic reactions have been reported. Only minor side effects were observed as follows.

    • Pain, redness or swelling at the injected area.
    • Facial flushing or paleness.
    • Headache, dizziness, nausea or vomiting.
    • Temporary redness of face and neck.
    • Depression.
    • Insomnia.
    • Gynecomastia.
    • Nerve sensitivity.
    • Hyperactivity.
    • Somnolence or drowsiness.
    • Sore bones.

    Should you experience allergic reactions or persistent and severe side effects as stated below, seek medical attention immediately

    • Hives (Urticaria), rash or skin itching
    • Difficulty breathing, difficulty swallowing (Dysphagia) or other upper respiratory conditions
    • Tightness or pain in the chest
    • Swelling of the mouth, face, lips, or tongue
  • Always inform your doctor or medical provider about your previous and existing health conditions including allergies, medicines, supplements or vitamins that you are currently taking or have taken previously to avoid any contraindications. If you are taking alcohol, using tobacco or any of the below medicines, inform your doctor right away:

    • Corticosteroids and thyroid medications
    • Cyclooxygenase inhibitors such as aspirin and indomethacin.
    • Glucocorticoids such as prednisone.
    • Insulin.
    • Medicines that lower thyroid levels such as propylthiouracil.
    • Muscarinic antagonists such as atropine.
    • Somatostatin-containing medicines or medicines that release somatostatin such as clonidine and levodopa.
    • Store away from heat, moisture, and light. Do not store in the bathroom.
    • Refrigerate Sermorelin between 36-46 °F or 2-8 °C at all times , inside a safe container, away from possible freezing or jostling.
    • GOnce mixed, use immediately.
    • Discard any unused portion of the vial.
    • Keep this product including syringes out of the reach of children and away from pets.